summary: A new study found that adults with hyperactivity and attention disorder show changes in the brain similar to those seen in the early stage, including high iron accumulation and increased nerve chain levels (NFL) in the blood. Using advanced MRI scanning and blood tests, researchers have determined the high iron in the main brain areas and signs of nerve damage in patients with hyperactivity disorder and attention lack compared to healthy individuals.
These signs are known for nervous degeneration diseases such as Alzheimer’s. The results indicate a potential biological mechanism linking ADHD to a more danger of dementia later in life, which confirms the importance of early ADHD diagnosis and intervention.
Main facts:
- Iron accumulation: Adults with hyperactivity and lack of attention have increased brain iron in areas associated with the cognitive function.
- Neuroscience index: High blood levels of the American Football Association, a sign of axial damage, are found in ADHD patients.
- Death link: A mixture of iron accumulation and the American Football Association indicates that ADHD may increase the risk of age -related dementia.
source: Geneva University
The adult brain that is affected by a lack of attention disorder with or without hyperplasim (ADHD) is similar adjustments to those observed in individuals with dementia.
These are the results of a study conducted by Geneva University Hospitals (HUG) and the University of Geneva (UNIGE) that show that, compared to healthy individuals, patients with hyperactivity disorder and attention disorder have more iron in certain areas of their brain along with higher levels of nervous family (NFL) in their blood.
These signs are constantly reported to be distinctive for old age dementia, such as Alzheimer’s and can be measured in its early stages.
The study confirms that ADHD may be associated with an increase in the risk of dementia later in life and that it provides a preliminary guide to a perhaps an included nervous mechanism.
This important step was described forward in the magazine Psychiatry and clinical nervous sciences.
Hyper movement disorder and attention lack is a frequent nervous growth disorder that affects about 3.5 % of adults according to the 2008 World Health Organization study (WHO). It is characterized by the inability to keep attention along with inappropriate levels of hyperactivity and impulsivity.
Although symptoms generally appear during childhood and greatly affect educational development and social interactions, their effects can continue and negatively affect daily performance in adults.
Old age -related dementia affects about 55 million people worldwide, with approximately 10 million new cases each year according to World Health Organization statistics from 2023. Alzheimer’s disease represents 60 to 70 % of these dementia.
“Recent epidemiological studies indicate that adults with hyperactivity disorder and attention lack have an increasing risk of dementia at an advanced age, but the mechanism through which hyperactivity disorder and attention lack is unknown,” says Professor in the Department of Psychiatry in the Department of Psychiatry in the Department of Psychiatry in the Department of Psychiatry in the Department of Psychiatry in the Department of Psychiatry in Psychiatry.
Iron and nerves such as indicators
The research team used the advanced brain imaging method, known as the QSM, through MRI to examine the iron content in the brain of 32 adults between the ages of 25 and 45 years of age affected by the hyperactivity disorder, lack of attention and 29 healthy individuals in the same age bow.
The levels of the nerve light chain protein (NFL) in the blood of the participants were measured in parallel.
The results of the study revealed noticeable differences in the distribution of iron in several areas of the brain of individuals affected by hyperactivity disorder and attention lack. Moreover, a great connection between iron levels was created at the levels of the previous cortex and the levels of the American Football Association in the blood.
Iron plays an essential role in the functioning of the normal brain, but its excessive accumulation may cause nerve cell damage and lead to neurological degenerative diseases such as Alzheimer’s disease.
“Excess iron is often observed in certain areas of the brain and is associated with an increase in oxidative stress that enhances nerve cell degeneration.”
Parallel, the American Football Association is an indication of damage to the neurons in the brain, and more specificly for the neuromus that are essential for the transmission of nerves. High blood levels of the American Football Association reflects the damage of a nervous axis in the brain.
Thus, increased levels of brain and NFL levels may indicate the basic neuropathic pathology and an increase in the risk of nervous degenerative dementia of old age.
These results confirm the existence of a link between hyperactivity disorder, lack of attention, increased threat of dementia in old age and identifying the first nerve mechanism.
The importance of early detection, hyperactivity disorder management and attention lack
These discoveries pave the way for the new research in understanding the reason for the increased risk of dementia.
Professor Paul uchult believes that the information provided by this study “will enable the development of targeted prevention strategies to reduce the risk of dementia in people with hyperactivity disorder and lack of attention. This is particularly important due to the presence of a well -known relationship between lifestyle and iron levels in the brain.
“To achieve this, additional longitudinal studies are needed to determine whether to reduce iron levels in the brain is a possible treatment pathway to prevent dementia at an advanced age in people with hyperactivity disorder and lack of attention.”
Moreover, the relationship between ADHD and dementia emphasizes the importance of early detection of these diseases. It also highlights the importance of ADHD proactive management in adults, not only to improve the quality of life for individuals but also to prevent long -term consequences for cognitive health.
Finance: This study was funded through a spark grant granted by the Swiss National Science Foundation (SNSF) to Professor Paul J.
On this dementia and ADHD research
author: Antoine Genot
source: Geneva University
communication: Antoine Genot – Geneva University
image: The image is attributed to news of neuroscience
The original search: Open access.
“Ironing brain load and nervous weakness in hyperactivity disorder in adult attentionWritten by Paul J. Unchang et al. Psychiatry and clinical nerve science
a summary
Ironing brain load and nervous weakness in hyperactivity disorder in adult attention
goal
ADHD’s hyperactivity disorder (ADHD) may be associated with an increased risk of dementia in aging. Here, we have investigated the responsibility for neurological brain disease in the disorder of hyperactivity and adult attention lack, and it may be reflected in the increase in iron content in the brain and the associated nervous weakness.
Blind
Thirty -two adults with hyperactivity disorder and attention lack (35 ± 10 years) and 29 identical controls between age and sex (32 ± 12 years) underwent MRI (MRI), uniform psychological testing and evaluation of lifestyle. Quantitative maps (QSM) has been used to assess magnetic deformities that indicate local changes in iron deposit in the brain.
By calculating the QSM maps, local iron deposition of the differences has statistically significant between hyperactivity disorder, attention lack and health controls. The levels of the nerve light chain in the plasma (NFL) were measured as an indicator of nervous safety using the fourth generation Ila Manna.
results
Iron content in the brain differed in people with hyperactivity disorder and attention lack, with the most powerful effects that can be observed in the previous right shell (health controls: 0.0033 ± 0.0017PM; Adhd: 0.0048 ± 0.0016PM; R.(59) = 3.56, p0.001). Moreover, the correct cortex iron has been associated with people with hyperactivity disorder and lack of attention to increased NFL levels in the blood (and(1.57) = 13.2, P =0.001, P2= 0.19).
conclusion
Our results indicate a change in regional iron content in adult brains with hyperactivity disorder and attention lack. The associated connection between the increase in previous magnetic sensitivity and the increase in the American Football Association indicates a link between the local surplus in the brain and neurological damage to the disorder of hyperactivity and attention lack.
Given the size of the limited sample of the current study and the natural medicine plan, more longitudinal studies are needed to determine whether the distribution of brain iron is changing in adults with hyperactivity disorder and attention deficit may be associated with an increase in the risk of dementia in aging.
2025-03-25 21:37:00
