summary: A new study reveals that even one night of sleep deprivation can change the features of the immune cells to resemble those seen in obesity, a condition related to chronic inflammation. Researchers have found that individuals deprived of sleep have increased the levels of monounsaic cells, and immune cells associated with inflammatory responses, similar to the patterns observed in the participants with obesity.
These results indicate that poor quality of sleep may quickly lead to the changes in the immune system, which may contribute to long -term inflammatory diseases such as obesity, diabetes and cardiovascular diseases. Future research will explore whether interventions such as organized sleep treatments can reflect these immune changes and improve public health.
Main facts
- Immunological sleep: One night of sleep deprivation changes immune cells, which mimics the inflammatory patterns seen in obesity.
- Inflammation: Sleep -deprived individuals have shown higher levels of non -classic monounsaturators, which regulate inflammatory responses.
- The risk of chronic diseases: Continuous sleep disorder may contribute to inflammatory dependence -based situations such as obesity, diabetes and heart disease.
source: Aai
A new search for an insight into the quality of sleep on a person’s immune system reveals, and how it can be linked to the development of diseases such as obesity, diabetes and cardiovascular diseases.
The study, published in Immunology Magazine, I found that until one night of sleep deprivation 24 hours in young individuals, lean, and sounds, I changed the image of immune cells that help organize the immune system to resemble those in individuals with obesity-a condition known for chronic inflammation.
This indicates that the immune system is very sensitive to sleep and may quickly adapt to the changes in the sleep pattern. According to researchers, if these transformations continue, they can contribute to long -term inflammatory cases and increase the risk of disease.
There is fundamental evidence linking sleep disorders and disorders with a group of chronic and sick conditions, such as type 2 diabetes and cardiovascular disease. It is also known that bad health results can be driven by chronic inflammation, but the direct effect of sleeping on circulating immune cells, such as mono cells, is not a good concept.
Monotropic cells are a vital component of the innate immune system – the first line of defense for the body that quickly detects pathogens and begins the immune response. There are three sub -groups of classic, medium and non -classical cells.
Non -classic uniforms do patrols in the body, feel and respond to inflammatory signals, and help maintain and regulate immune response.
In this study, the researchers from the Dasman Institute for Diabetes, Kuwait City, Kuwait, analyzed sleep patterns of 237 good health participants in the various body mass index, and took blood samples for the acts of different levels of unitia as well as signs of infections.
They found that individuals with obese have a much lower sleep quality and chronic low -quality inflammation compared to the meager group.
Non -classic unlikes have also been dramatically increased in obese participants, and are associated with low sleep quality and infection signs.
Five, and healthy, healthy individuals also participated in a 24 -hour sleep deprivation, and blood samples were collected throughout.
The researchers found that sleep deprivation other than monounsorphic profile, such as what was seen in obese participants, and supporting the role of sleep health in adjusting inflammation.
“The results we have reached stress the growing general health challenge. Developments in technology, the lengthy screen time, and the conversion of societal standards have become increasingly turbulent for normal sleep hours.
“This sleep disturbance has deep effects on immunity health and general well -being.”
The researchers then want to explore the mechanisms of sleep deprivation with immune changes in more detail. They also want to know if interventions such as organized sleep treatments or technology use instructions can reflect these immune changes.
“In the long term, we aim to lead this research to advance the policies and strategies that recognize the decisive role of sleeping in public health. We imagine reforms in the workplace and educational campaigns that enhance better sleep practices, especially for the population at risk of disrupting sleep due to technological and professional demands.
“In the end, this can help relieve the burden of inflammatory diseases such as obesity, diabetes and cardiovascular diseases,” said Dr. Rashid.
About this sleep and inflammatory research news
author: Lam died
source: Aai
communication: Matt Lam – AII
image: The image is attributed to news of neuroscience
The original search: Open access.
“The effect of sleep deprivation on mono -cell and functional sub -categoriesBy Fatema al-Rashed et al. Immunology Magazine
a summary
The effect of sleep deprivation on mono -cell and functional sub -categories
The relationship between sleep deprivation, obesity and systemic infections is a decisive field in the investigation due to its great impact on health. Although it is fixed that bad sleep negatively affects obesity syndromes and metabolism, the specific mechanisms, especially inflammation without clinical independent of obesity, are still unclear.
This study is looking at how sleep quality affects the distribution of a single -cell sub -group and its association with peripheral inflammation through a group of body mass index categories.
In our dust study, 237 healthy participants were classified according to the BMI. Eating of food participants, physical activity, and objective patterns are tracked through the Actigraph GT3X acceleration scale that can be worn.
Data showed that obese individuals have a significant decrease in sleep quality and low inflammation of chronic quality. Non -classic only increased in obesity, linked to low sleep quality and high inflammatory cytokines.
Although the body mass index appeared as an important factor in leading the inflammation, the mediation analysis determined that the sleep disabling contributes independently to inflammation, regardless of the condition of obesity.
The experiments of deprivation of the controlled sleep confirmed these results, which indicates adverse increases in the expression of monounsaturated cells.
This study highlights the importance of sleep quality in organizing immune responses and infection in obesity, indicating that improving the quality of sleep can reduce inflammation and improve health results.
2025-02-24 23:18:00
